Posted:2019-11-06 Visits:
Address: State Key Laboratory of Physical Chemistry of Solid Surfaces
l Ph.D., Shanghai Institute of Organic Chemistry, Shanghai, China (2014)
l Post-Doctor, Max-Planck-Institut für Kohlenforschung, Germany (2014-2019)
l Professor, Xiamen Univ. (2019- )
Development of novel methodology for organic synthesis; asymmetric catalysis; syntheses of bioactive natural products and drugs
1. Catalysis-based total syntheses of pateamine A and DMDA-Pat A. J. Am. Chem. Soc. 2018, 140, 10514–10523.
2. Concise synthesis of a pateamine A analogue with in vivo anticancer activity based on an iron catalyzed pyrone ring-opening/cross coupling. Angew. Chem. Int. Ed. 2016, 55, 6051-6056.
3. Enantioselective construction of spiroindolines with three contiguous stereogenic centers and chiral tryptamine derivative via the reactive spiroindolenine intermediates. Angew. Chem. Int. Ed. 2015, 54, 14146-14149.
4. Highly regio- and enantioselective synthesis of poly-substituted 2H-pyrroles via Pd-catalyzed intermolecular asymmetric allylic dearomatization of pyrroles. J. Am. Chem. Soc. 2014, 136, 6590-6593.
5. Enantioselective functionalization of indoles and pyrroles via an in-situ formed spiro-intermediate. J. Am. Chem. Soc. 2013, 135, 8169-8172.