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科研进展:Electrochemical C−H/N−H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles

发布日期:2016年06月03日   浏览次数:


我室徐海超教授和吕鑫教授在Angew. Chem. Int. Ed.上发表了题为'Electrochemical C−H/N−H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles'的研究论文。
相关链接:
http://onlinelibrary.wiley.com/doi/10.1002/anie.201602616/full

Abstract

Indoles and azaindoles are among the most important heterocycles because of their prevalence in nature and their broad utility in pharmaceutical industry. Reported herein is an unprecedented noble-metal- and oxidant-free electrochemical method for the coupling of (hetero)arylamines with tethered alkynes to synthesize highly functionalized indoles, as well as the more challenging azaindoles.