Title: Ionic Liquid Supported (ILS) Chiral Catalysts for Asymmetric Organic Reactions in Aqueous Media

Speaker: Dr. Bukuo Ni, Department of Chemistry, Texas A&M University-Commerce, Commerce, Texas 75429-3011, United States

Date: 2019-06-10 10:30AM

Location: Room 202, Lujiaxi Building

Abstract：

The asymmetric synthesis of chiral compounds that contain new C-C and C-O bonds remains one of the most important types of synthesis in organic chemistry. Over the years, many different types of catalysts have been designed and used effectively to carry out such transformation. This talk will introduce the development of a novel class of ILS chiral pyrrolidine-based organocatalysts for the asymmetric organic reactions, including Michael addition, Aldol reaction, and domino reactions, in aqueous media providing the desired products with high stereoselectivity. In addition, the ILS chiral diamine ligands will also be introduced and used with transition metals Rh and Ir as catalysts for asymmetric transfer hydrogenation of ketones and α-keto phosphonates in water. This process provided the corresponding chiral secondary alcohol products in high enantioselectivity.

Biography:

EDUCATION/DEGREES 

2004 Ph. D. in Organic Chemistry Shanghai Institute of Organic Chemistry (SIOC) Chinese Academy of Sciences, Shanghai, China

1999 B.S. in Chemistry Department of Chemistry, Zhejiang University, Hangzhou, China      

PROFESSIONAL EXPERIENCE

Fall, 2018-Current Associate Professor Department of Chemistry, TAMU-Commerce

Fall, 2012-Spring, 2018    Assistant Professor Department of Chemistry, TAMU-Commerce

Fall, 2010- Spring, 2012   Interim Assistant Professor Department of Chemistry, TAMU-Commerce

Jan. 2008 - Aug. 2010 Research Assistant Professor Department of Chemistry, TAMU-Commerce

Jan. 2005 - Dec. 2007 Postdoctoral Researcher  Department of Chemistry, TAMU-Commerce

July 2004- Jan. 2005 Senior Scientist Sundia (Shanghai) MedTech Company Ltd. Shanghai, China